Anholt2014 - Age of onset in obsessive-compulsive disorder, admixture analysis with a large sample

  • Type:#article
  • Year read:#read2022
  • Subject: OCD
  • Bibtex: @anholt2014
  • Bibliography: Anholt, G. E., Aderka, I. M., van Balkom, A. J. L. M., Smit, J. H., Schruers, K., van der Wee, N. J. A., Eikelenboom, M., De Luca, V., & van Oppen, P. (2014). Age of onset in obsessive–compulsive disorder: Admixture analysis with a large sample. Psychological Medicine, 44(1), 185–194.

Example citation

OCD has a bimodal onset, with early onset OCD (mean age 13) shows a more severe clinical presentation compared to late onset (mean age 25) of the disorder [@anholt2014].

Key takeaways

  • Admixture analysis was used to determine the best representation of the data distribution.
  • n = 377
  • Bimodal age of onset, best split was at 20 years old. Patients with early onset (≤19 years old) had more severe OCD and comorbid presentations.
  • Early onset, mean = 12.82 (95% CI 11.18 to 14.46) years old
  • Late onset, mean = 24.90 (95% CI 21.30 to 28.50) years old