- Year read:#read2022
- Subject: OCD
- Bibtex: @brander2016a
- Bibliography: Brander, G., Rydell, M., Kuja-Halkola, R., Cruz, L. F. de la, Lichtenstein, P., Serlachius, E., Rück, C., Almqvist, C., D’Onofrio, B. M., Larsson, H., & Mataix-Cols, D. (2016). Association of Perinatal Risk Factors With Obsessive-Compulsive Disorder: A Population-Based Birth Cohort, Sibling Control Study. JAMA Psychiatry, 73(11), 1135–1144. https://doi.org/10.1001/jamapsychiatry.2016.2095
Multiple perinatal risk factors are associated with OCD (e.g., maternal smoking during pregnancy, low birth weight, delivery by cesarean section) after controlling for shared familial confounders, and there is a dose-response association between the number of perinatal evens and OCD risk [@brander2016a].
- Exposures: maternal smoking during pregnancy, labor presentation, obstetric delivery, gestational age, birth weight, Apgar score, head circumference
- Control for shared familial confounders and sex, year of birth, maternal and paternal age at birth, and parity.
- Risk factors: Smoking ≥10 cigarettes per day during pregnancy, breech presentation, delivery by cesarean section, preterm birth, low birth weight, and Apgar distress scores.
- Dose-response association between the number of perinatal events and increased OCD risk.