Cederlöf2015 - Etiological overlap between obsessive-compulsive disorder and anorexia nervosa. a longitudinal cohort, multigenerational family and twin study
- Year read:#read2022
- Subject: OCD
- Bibtex: @cederlof2015
- Bibliography: Cederlöf, M., Thornton, L. M., Baker, J., Lichtenstein, P., Larsson, H., Rück, C., Bulik, C. M., & Mataix-Cols, D. (2015). Etiological overlap between obsessive-compulsive disorder and anorexia nervosa: A longitudinal cohort, multigenerational family and twin study. World Psychiatry, 14(3), 333–338. https://doi.org/10.1002/wps.20251
The high degree of co-occurrence between OCD and anorexia nervosa can in part be explained by shared genetic factors [@cederlof2015]
- National Patient Register. OCD (n = 19814) and AN (n = 8462)
- Females with OCD had OR = 16 for AN-diagnosis, for males it was higher at OR = 37.
- Relatives of patients with OCD had increased risk for AN, and the magnitude varied with genetic relatedness.
- Genetic overlap between (self-report) OCD and (diagnosed) AN, r = 0.52 (95% CI 0.26 to 0.81). BUT specific genetic influences more important.