Farris2013 - Treatment Response, Symptom Remission, and Wellness in Obsessive-Compulsive Disorder


Example citation

The Y-BOCS has a high accuracy identifying treatment responders and remitters [@farris2013].

Key takeaways

  • n = 288, four different trials
  • Y-BOCS improvement ≥35% was best cut-off for response (CGI-I of 1 or 2)
    • Sens 0.9, Spec 0.94
    • PPV 0.94, NPV 0.9
    • K = 0.84
  • Y-BOCS score ≤14 was best cut-off for remission (CGI-S 1 to 3)
    • Sens 0.93, Spec 0.98
    • PPV 0.97, NPV 0.95
    • K = 0.91
  • Y-BOCS score ≤12 was best cut-off for wellness (CGI-S 1 to 3 + good quality of life and functioning)
    • Sens 0.78, Spec 0.88
    • PPV 0.57, NPV 0.95
    • K = 0.57