Mataix-Cols2013 - Population-Based, Multigenerational Family Clustering Study of Obsessive-Compulsive Disorder

  • Type:#article
  • Year read:#read2022
  • Subject: OCD
  • Bibtex: @mataix-cols2013
  • Bibliography: Mataix-Cols, D., Boman, M., Monzani, B., Rück, C., Serlachius, E., Långström, N., & Lichtenstein, P. (2013). Population-based, multigenerational family clustering study of obsessive-compulsive disorder. JAMA Psychiatry, 70(7), 709–717. https://doi.org/10.1001/jamapsychiatry.2013.3

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Key takeaways

  • Risk for OCD among relatives increased proportionally to the degree of genetic relatedness.
  • Heritability 47% (95% CI 42% – 52%)
  • OCD clusters in families due to genetic factors, not shared environment.