- Year read:#read2021
- Subject: (in brackets, can also bracket keywords in text)
- Bibtex: @morgan2019
- Bibliography: Morgan, C. J. (2019). Landmark analysis: A primer. Journal of Nuclear Cardiology, 26(2), 391–393. https://doi.org/10.1007/s12350-019-01624-z
Landmark analysis is when you select a time point during follow-up and analyze only the subjects who have survived until the landmark time.
It is used to avoid guarantee-time bias where responders are guaranteed to survive until the time of response.
- Landmark analysis is a useful sensitivity analysis in survival analysis studies
- Pick the landmark carefully or use multiple landmarks
- There is an extension of the Cox proportional hazard models called a time-varying Cox model that can be used as an alternative, but results are hard to interpret.