• Type:#article
  • Date read: 2022-07-07
  • Subject: Depression
  • Bibtex: @otto2022
  • Bibliography: Otto, M. W., Birk, J. L., Fitzgerald, H. E., Chauvin, G. V., Gold, A. K., & Carl, J. R. (2022). Stage models for major depression: Cognitive behavior therapy, mechanistic treatment targets, and the prevention of stage transition. Clinical Psychology Review, 95, 102172. https://doi.org/10.1016/j.cpr.2022.102172

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Key takeaways

  • Stage models means taking a longitudinal perspective. How can we identify and prevent stage transitions in depression? Can CBT be used?
    • Not just symptom reduction but also being proactive
  • Insomnia and rumination are key mechanisms propelling stage transitions in depression, trans-stage meaning across all different stages!
    • They are particularly important treatment targets if this is true.
  • They review the impact of insomnia on mood:
    • Stronger emotional reactions to negative stimuli
    • Impaired emotion regulation
    • More negative emotional memories
  • Impact of rumination (Response Styles Theory by Nolen-Hoeksema)
    • Increases in mood-congruent thinking
    • Decreases in problem-solving and instrumental behavior
    • Decreases in social support
  • Rumination is a trans-diagnostic style of thinking in psychopathology

When applied to psychiatric disorders, stage models reflect the progression from prodromal symptoms to full episodes, to recurrent episodes of greater severity, and finally to treatment resistance.