Posner2017 - Increased Functional Connectivity between the Default Mode and Salience Networks in Unmedicated Adults with Obsessive-Compulsive Disorder

  • Type:#article
  • Year read:#read2022
  • Subject: OCD
  • Bibtex: @posner2017
  • Bibliography: Posner, J., Song, I., Lee, S., Rodriguez, C. I., Moore, H., Marsh, R., & Blair Simpson, H. (2017). Increased functional connectivity between the default mode and salience networks in unmedicated adults with obsessive-compulsive disorder: Default Mode and Salience Networks in OCD. Human Brain Mapping, 38(2), 678–687. https://doi.org/10.1002/hbm.23408

Example citation

Unmedicated OCD-patients show alterations in functional connectivity between the default mode and salience networks, which contributes to decreased sustained attention in OCD [@posner2017].

Key takeaways

  • OCD patients (n = 30) and healthy controls (n = 32) were compared on functional connectivity, default mode network vs salience network.
  • OCD symptoms associated with an imbalance between the default mode and salience networks, which has a negative impact on sustained attention.
  • Conner’s Continuous Performance Test (the one I used with ADHD children at KIND)