Smit2020 - Genetic meta-analysis of obsessive-compulsive disorder and self-report obsessive-compulsive symptoms

  • Type:#article
  • Year read:#read2022
  • Subject: OCD Genetics
  • Bibtex: @smit2020
  • Bibliography: Smit, D. J. A., Cath, D., Zilhão, N. R., Ip, H. F., Denys, D., Braber, A., Geus, E. J. C., Verweij, K. J. H., Hottenga, J., & Boomsma, D. I. (2020). Genetic meta‐analysis of obsessive–compulsive disorder and self‐report compulsive symptoms. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 183(4), 208–216.

Example citation

Compulsive symptoms in the general population are genetically correlated with OCD [@smit2020].

Key takeaways

  • Short-version of the Padua inventory used for GWAS, n = 8267
  • Compulsive sub-scale had a strong correlation with OCD PRS (r = 0.61), but not obsessions sub-scale (r = -0.02) and total score (r = 0.42) on the Padua Inventory.
  • three