Yilmaz2022 - The role of early-life family composition and parental socio-economic status as risk factors for obsessive-compulsive disorder in a Danish national cohort
- Type:#article
- Year read:#read2022
- Subject: OCD
- Bibtex: @yilmaz2022
- Bibliography: Yilmaz, Z., Larsen, J. T., Nissen, J. B., Crowley, J. J., Mattheisen, M., Bulik, C. M., & Petersen, L. V. (2022). The role of early-life family composition and parental socio-economic status as risk factors for obsessive-compulsive disorder in a Danish national cohort. Journal of Psychiatric Research, 149, 18–27. https://doi.org/10.1016/j.jpsychires.2022.02.004
Example citation
Indicators of socioeconomic stress, for example one more parents outside the labour market or living with only one parent, are associated with a higher risk of OCD [@yilmaz2022].
Key takeaways
- Danish population registry, n = 7550 with OCD
- Birth order and higher maternal age were risk factors for OCD in males, being an only child was a risk factor for OCD in both sexes.
- Parental education, occupation and income were associated with OCD risk, particularly in females
Data on early-life family composition (birth order, number of siblings, number of parents in household at proband age 6), parental SES at age 6 (parental income, occupation, and education level), history of parental psychiatric illness, and parental age at birth on OCD risk (i.e., an ICD-10 diagnosis of F42.x) were obtained from Danish population registers.
Specifically, at least one parent having high in come was associated with lower OCD risk in the combined sample and females. Low-income level for both parents was associated with increased OCD risk in females in the sex-stratified analysis, and this trend was also present in the association between having both parents outside labor market at age 6 and a higher likelihood of OCD diagnosis. The only significant differential effect for sex was observedfor having at least one parent with long-term higher education (i.e., a bachelor’s degree or higher), which was associated with significantly decreased OCD risk in the combined sample as well as in females.